Megaloblastic Anaemia of Infancy Treated with Folic Acid

Megaloblastic anaemia in coeliac disease treated with folic acid.

Changes in serum vitamin B12 levels in patients with megaloblastic anaemia treated with folic acid.

In 21 patients with megaloblastic anaemia associated with the tropical malabsorption syndrome serum vitamin B(12) levels have been measured serially before and during parenteral folic acid therapy. In 11 patients there was a significant rise in serum B(12) levels, reaching a peak three to 17 days after starting the folic acid. In three of these cases, absorption of labelled B(12) was the same b...

Megaloblastic anaemia of infancy in Jamaica.

Anaemia in infancy responding specifically to haemopoietic factors present in liver is not common. Between the years 1946 and 1953 a considerable number of cases was reported from the United States of America (Zuelzer and Ogden, 1946) and Italy (Amato, 1946; Pecorella, Burgio and Aversa, 1947). The literature up to 1953 is fully reviewed by Zuelzer and Rutzky (1953). Since that time reports hav...

Megaloblastic Anaemia Complicating Dietary Treatment of Phenylketonuria in Infancy.

Nutritional deficiencies may complicate the treatment of phenylketonuria by 'synthetic' phenylalanine restricted diets. This danger is greatest in infancy when growth is rapid. We report the occurrence of megaloblastic anaemia of infancy due to folic acid deficiency, during the dietary treatment of a baby with phenylketonuria. Case Report Simon B. was born at home on July 16, 1960, the third ch...

Extensive myeloid response during folic acid therapy in megaloblastic anaemia of pregnancy.

The patient, aged 29 years, para 3, unmarried, and of subnormal intelligence, was first seen in the thirtyfourth week of pregnancy at the hospital antenatal clinic. Previous pregnancies were uneventful and there was no record of serious illnesses. The family history was irrelevant. The present pregnancy progressed uneventfully until early in the sixth month when she had a severe haemorrhage fro...