Medications to Prevent HIV Infection

Failure to prevent perinatal HIV infection.

Prospects for passive immunity to prevent HIV infection

In a Perspective, Lynn Morris and Nonhlanhla Mkhize discuss the prospects for broadly neutralizing antibodies to be used in preventing HIV infection.

Intravaginal and intrarectal microbicides to prevent HIV infection.

Interventions against sexually transmitted infections (STI) to prevent HIV infection.

STIs have taken on a more important role with the advent of the HIV/AIDS epidemic, and there is good evidence that their control can reduce HIV transmission. The challenge is not just to develop new interventions, but to identify barriers to the effective implementation of existing tools, and to devise ways to overcome these barriers. This 'scaling-up' of effective strategies will require an in...

Cost-effective allocation of government funds to prevent HIV infection.

Relative to the magnitude of the epidemic, government funds available for HIV prevention are scarce. To optimize use of funds, we applied a mathematical model of the cost of HIV prevention interventions using national data on HIV risk-group size and HIV prevalence. This procedure suggested an allocation of funds across nine interventions to potentially prevent an estimated 20,000 infections ann...