Medical Treatment of Peptic Ulcer

Medical management of peptic ulcer.

Sir Francis Avery Jones (FAJ-for once the abbreviation means something to everyone) has been actively involved in the practical and research aspects of management of peptic ulcer throughout his long and productive career. Some of FAJ's earliest publications (Avery Jones, 1939a and b, 1943, 1947) deal with management of acute upper alimentary bleeding and he was instrumental in introducing moder...

The Treatment of Peptic Ulcer

Treatment of Peptic Ulcer Disease

For more than a century, peptic ulcer disease has been a major cause of morbidity and mortality. In the early part of the 20th century, when stress and diet were judged to be important pathogenetic factors for peptic ulceration, patients with peptic ulcers were treated with hospitalization, bed rest, and the prescription of “bland” diets. By the 1950s, investigators and clinicians had focused t...

Medical aspects of chronic peptic ulcer.

General Considerations Few diseases, whether from their frequency of incidence or their difficulties in treatment, can claim a more rightful place in medical attention than peptic ulcer, a comment applying with equal force to physician and to surgeon, and to hospital as well as to general practice. Figures of hospital emergency admissions show few conditions more demanding on the medical side t...

Treatment of refractory peptic ulcer with omeprazole

Accepted for publication 14 May 1990 Abstract We tested the hypothesis that the gastric H+/K+ adenosine triphosphatase inhibitor, omeprazole, because of its different mode of action and pronounced inhibitory effect on gastric acid secretion, may be more effective in peptic ulcer that is refractory to histamine H2 receptor antagonist treatment than continuing the same therapy. Altogether 107 pat...