Medical Therapy in Adults With Fibrous Dysplasia of Bone
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چکیده
منابع مشابه
Fibrous Dysplasia of Bone
Fibrous dysplasia is a disease which may be manifested in a single bone as tumefaction or a solitary cyst (monostotic type), in a region involving contiguous bones, or in a diffuse manner (polyostotic type), the latter possibly in association with endocrine and developmental disturbances. The condition is of interest to the neurological surgeon when the cranial or cranio-facial structures are i...
متن کاملOsteoclastogenesis in fibrous dysplasia of bone pdf
Fibrous dysplasia of bone FD is caused by somatic mutations of the GNAS1. Here, patterns of osteoclastogenesis and bone resorption reflect not only the.FIBROUS DYSPLASIA FD is a sporadic developmental disorder characterized by. Biochemical indices of bone turnover are usually high particularly serum. Osteoclasts within the lesions is slightly higher than normal and the number of.Introduction: F...
متن کاملBone-Grafting in Polyostotic Fibrous Dysplasia.
BACKGROUND Polyostotic fibrous dysplasia is a skeletal disease that results from somatic activating mutations in the gene GNAS in skeletal stem cells, leading to proliferation of immature osteogenic cells with replacement of normal marrow and bone with fibro-osseous tissue. Lesions may cause bone deformity or fracture. In the surgical care of polyostotic fibrous dysplasia, the role of grafting ...
متن کامل[3 cases of fibrous dysplasia of bone].
Clinical history and examination A TWENTY-FOUR year old soldier was seen on 4 March 1969 with a two month history of cramp-like pains in the right thigh and front of right leg. Pain was intermittent, aggravated by standing for more than a half hour, or walking more than a half mile. Five years ago he had received a direct blow to the right tibia in a traffic accident and since then he had notic...
متن کاملCraniofacial Fibrous Dysplasia
Fibrous dysplasia (FD) is an osseous growth dis-order, producing immature bone and characte-rized by the replacement of normal bone with fibro-osseous connective tissue. It is a bone dys-plasia that has the potential to cause significant cosmetic and functional disturbances, particularly in the craniofacial skeleton. Cra-niofacial fibrous dysplasia is one of the three types of polyostotic fibro...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2006
ISSN: 0884-0431
DOI: 10.1359/jbmr.06s222