Mechanotransduction in skeletal muscle
نویسندگان
چکیده
منابع مشابه
Mechanotransduction in skeletal muscle.
Mechanical signals are critical to the development and maintenance of skeletal muscle, but the mechanisms that convert these shape changes to biochemical signals is not known. When a deformation is imposed on a muscle, changes in cellular and molecular conformations link the mechanical forces with biochemical signals, and the close integration of mechanical signals with electrical, metabolic, a...
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The majority of cells are equipped to detect and decipher physical stimuli, and then react to these stimuli in a cell type-specific manner. Ultimately, these cellular behaviors are synchronized to produce a tissue response, but how this is achieved remains enigmatic. Here, we investigated the genetic basis for mechanotransduction using the bone marrow as a model system. We found that physical s...
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ژورنال
عنوان ژورنال: Frontiers in Bioscience
سال: 2007
ISSN: 1093-9946,1093-4715
DOI: 10.2741/2057