Mechanisms of Resistance to Photodynamic Therapy
نویسندگان
چکیده
منابع مشابه
Mechanisms of Resistance to Photodynamic Therapy: An Update
© Springer International Publishing Switzerland 2015 V. Rapozzi, G. Jori (eds.), Resistance to Photodynamic Therapy in Cancer, Resistance to Targeted Anti-Cancer Therapeutics 5, DOI 10.1007/978-3-319-12730-9_2 A. Casas () · C. Perotti · G. Di Venosa · A. Batlle Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP), CONICET and Hospital de Clínicas José de San Martín, University of Bue...
متن کاملMolecular mechanisms of photodynamic therapy.
Despite its more than 100-year history in experimental and clinical use, photodynamic therapy (PDT) is only starting to be appreciated for its full potential. PDT combines a photosensitizer (PS) and light in the presence of oxygen to treat cancer and other disorders. This manuscript reviews molecular mechanisms that have been evaluated over the past years for the effects of PDT at the cellular ...
متن کاملMelanoma resistance to photodynamic therapy: new insights.
Melanoma is the most dangerous form of skin cancer, with a steeply rising incidence and a poor prognosis in its advanced stages. Melanoma is highly resistant to traditional chemotherapy and radiotherapy, although modern targeted therapies such as BRAF inhibitors are showing some promise. Photodynamic therapy (PDT, the combination of photosensitizing dyes and visible light) has been tested in th...
متن کاملPhotodynamic Therapy (PDT): PDT Mechanisms
Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in oncology a photosensitizing agent is applied and then activated by a specific wavelength and energy of light. This light energy in the presence of oxygen will lead to the creation of the photodynamic reaction which is cyto and vasculo toxic. This paper will review the mechanisms of action of PDT and how t...
متن کاملGlycol porphyrin derivatives and temoporfin elicit resistance to photodynamic therapy by different mechanisms
The development of drug resistance is a major problem which often occurs during anticancer chemotherapies. Photodynamic therapy (PDT) has been studied as an alternative treatment modality for drug-resistant tumors, however the question of resistance to PDT and potential cross-resistance with chemotherapy has yet to be fully answered. To investigate the mechanism of resistance to PDT, we develop...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Medicinal Chemistry
سال: 2011
ISSN: 0929-8673
DOI: 10.2174/092986711795843272