MECHANISMS OF RECOVERY FROM A GENERALIZED VIRAL INFECTION: MOUSEPOX
نویسندگان
چکیده
منابع مشابه
Mechanisms of Recovery from a Generalized Viral Infection: Mousepox
The following passive transfer experiments evaluated the contributions of the various host responses in recovery from mousepox. (a) Immune spleen cells transferred highly efficient antiviral activity, but preinfected recipients of these cells made no detectable splenic interferon or antibody in the 24 hr interval after cell transfer. (b) Passively administered interferon was ineffective. (c) Re...
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Poxviruses subvert the host immune response by producing immunomodulatory proteins, including a complement regulatory protein. Ectromelia virus provides a mouse model for smallpox where the virus and the host's immune response have co-evolved. Using this model, our study investigated the role of the complement system during a poxvirus infection. By multiple inoculation routes, ectromelia virus ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1971
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.133.5.1090