Mechanisms of phagocytic host defense against Pseudallescheria boydii (Scedosporium apiospermum): an emerging polyene-resistant fungal pathogen in immunocompromised hosts
نویسندگان
چکیده
منابع مشابه
Human phagocytic cell responses to Scedosporium apiospermum (Pseudallescheria boydii): variable susceptibility to oxidative injury.
Scedosporium apiospermum (Pseudallescheria boydii) is an emerging opportunistic filamentous fungus that causes serious infections in both immunocompetent and immunocompromised patients. To gain insight into the immunopathogenesis of infections due to S. apiospermum, the antifungal activities of human polymorphonuclear leukocytes (PMNs), mononuclear leukocytes (MNCs), and monocyte-derived macrop...
متن کاملVoriconazole-Resistant Penicillium oxalicum: An Emerging Pathogen in Immunocompromised Hosts
Penicillium species are rarely reported agents of infections in immunocompromised patients. We report 3 cases of invasive mycosis caused by voriconazole-resistant Penicillium oxalicum in patients with acute myeloid leukemia, diabetes mellitus, and chronic obstructive pulmonary disease, while on voriconazole therapy. Penicillium oxalicum has not been previously recognized as a cause of invasive ...
متن کاملSusceptibility of Pseudallescheria boydii and Scedosporium apiospermum to new antifungal agents.
Hyalohyphomycoses caused by Pseudallescheria boydii and Scedosporium apiospermum have recently been on the increase. To find the appropriate treatment for this emerging disease, we examined the antifungal susceptibility of 10 isolates of P. boydii and 17 isolates of S. apiospermum, most of which were isolated from clinical specimens. When the NCCLS M38-P microdilution method was used, itraconaz...
متن کاملPseudallescheria Boydii pneumonia in an immunocompetent host
BACKGROUND Pseudallescheria boydii pneumonia is rarely reported among immunocompetent patients. CASE REPORT We report a case of a 62 year old white female with pseudallescheria boydii pneumonia. The patient was non-immunocompromised, had a history of mycobacterium avium complex (MAC) infection prior to presentation. After successful response to initial antitubercular therapy, the patient deve...
متن کاملCandida auris, an Emerging Fungal Pathogen
The emerging pathogen “Candida auris” is attracting considerable international attention due to its rising reports, transmission through health professionals, high rate of treatment failure and resistance to multiple antifungal agents, particularly fluconazole. In spite of the global emergence of C. auris, epidemiological data and true prevalence of infections due to this organism are not clear...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2002
ISSN: 1201-9712
DOI: 10.1016/s1201-9712(02)90282-1