Mechanisms of malignant progression
نویسندگان
چکیده
منابع مشابه
Mechanisms of malignant progression.
While a coherent picture has begun to emerge about the biological and molecular mechanisms that create primary tumors, the processes that lead subsequently to invasion and metastasis have, until recently, been relatively obscure. However, over the past 5 years, research of diverse sorts has begun to generate the conceptual outlines that explain how high-grade malignancies arise. These discussio...
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tory, although the time course may be quite variable. This phenomenon has been termed tumor progression, and Foulds (1,2) first pointed out that the process appears to develop in a stepwise fashion through qualitatively different stages. Others, including the author, have subsequently suggested that this biological and clinical progression might reflect, at least in part, the sequential appeara...
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ژورنال
عنوان ژورنال: European Journal of Cancer Supplements
سال: 2008
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(08)71422-8