Mechanisms Mediating Functional Hyperemia in the Brain
نویسندگان
چکیده
منابع مشابه
Mechanisms Mediating Functional Hyperemia in the Brain.
Neuronal activity within the brain evokes local increases in blood flow, a response termed functional hyperemia. This response ensures that active neurons receive sufficient oxygen and nutrients to maintain tissue function and health. In this review, we discuss the functions of functional hyperemia, the types of vessels that generate the response, and the signaling mechanisms that mediate neuro...
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متن کاملFunctional hyperemia and mechanisms of neurovascular coupling in the retinal vasculature.
The retinal vasculature supplies cells of the inner and middle layers of the retina with oxygen and nutrients. Photic stimulation dilates retinal arterioles producing blood flow increases, a response termed functional hyperemia. Despite recent advances, the neurovascular coupling mechanisms mediating the functional hyperemia response in the retina remain unclear. In this review, the retinal fun...
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BACKGROUND Cerebral blood flow is tightly coupled to neuronal metabolic activity, a phenomenon referred to as functional hyperemia. The mechanisms underlying functional hyperemia in the brain have been extensively studied, but the link between neuronal activation and nutritive blood flow has yet to be defined. Recent investigations by our laboratory and others have identified a potential role f...
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ژورنال
عنوان ژورنال: The Neuroscientist
سال: 2017
ISSN: 1073-8584,1089-4098
DOI: 10.1177/1073858417703033