Mechanisms for mechanical damage in the intervertebral disc annulus fibrosus
نویسندگان
چکیده
منابع مشابه
Analysis of Selected Mechanical Properties of Intervertebral Disc Annulus Fibrosus in Macro and Microscopic Scale
The main goal of this paper is experimental analysis of selected mechanical properties of single annulus fibrosus lamellae at macroscopic and microscopic levels as well as representation and explanation of the structural response to forced deformation. The conducted analysis of single annulus fibrosus lamella with preserved natural attachments revealed two characteristic mechanisms leading to d...
متن کاملEffect of Annulus Fibrosus Collagen Orientation on Intervertebral Disc Torsional Mechanical Behavior
INTRODUCTION: Intervertebral disc experiences large complex deformations including compression, rotation, and bending under daily activity. For example, twisting while carrying a weight, loads the disc under axial compression and axial rotation. Previous work showed that the rate of degeneration and disc injury is higher for in workers that experience repetitive twisting and lifting [1]. Disc d...
متن کاملExperimental Application of Bone Marrow Mesenchymal Stem Cells for the Repair of Intervertebral Disc Annulus Fibrosus
BACKGROUND This study provides experimental results on the applicability of bone marrow mesenchymal stem cells (BMSCs) for the repair of intervertebral disc annulus fibrosus in rabbits. MATERIAL AND METHODS Thirty healthy rabbits were randomized into an observation group (n=15) and a control group (n=15). Both groups underwent degeneration of intervertebral disc annulus fibrosus. The observatio...
متن کاملCollagen fibrillogenesis in the development of the annulus fibrosus of the intervertebral disc.
The annulus fibrosus of the intervertebral disc is a complex, radial-ply connective tissue consisting of concentric lamellae of oriented collagen. Whilst much is known of the structure of the mature annulus, less is known of how its complex collagenous architecture becomes established; an understanding of which could inform future repair/regenerative strategies. Here, using a rat disc developme...
متن کاملThe effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus.
BACKGROUND CONTEXT Needle puncture of the intervertebral disc (IVD) is required for delivery of therapeutic agents to the nucleus pulposus and for some diagnostic procedures. Needle puncture has also been implicated as an initiator of disc degeneration. It is hypothesized that needle puncture may initiate IVD degeneration by altering microscale mechanical behavior in the annulus fibrosus (AF). ...
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ژورنال
عنوان ژورنال: Journal of Biomechanics
سال: 2004
ISSN: 0021-9290
DOI: 10.1016/j.jbiomech.2003.12.026