Mechanical Threshold As a Factor in Excitation-Contraction Coupling
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Mechanical Threshold As a Factor in Excitation-Contraction Coupling
I(-), CH(3)SO(4) (-), and ClO(4) (-), like other previously studied type A twitch potentiators (Br(-), NO(3) (-), SCN(-), and caffeine), lower the mechanical threshold in K depolarization contractures of frog skeletal muscle. In potentiated twitches, I(-), Br(-), CH(3)SO(4) (-), ClO(4), and SCN, as already reported for NO(3) (-) and caffeine, slightly shorten the latent period (L) and considera...
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T HE PRIMARY task of heart muscle is to develop force and shorten at regular intervals. The action potential is the initial step in triggering contraction of the heart, and it may also be an important regulator of contraction strength. The process that links this membrane electrical event to the contraction is given the broad name of excitation-contraction coupling. The more we have increased o...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1969
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.54.3.352