Mechanical Desorption of Single Fibronectin Type III Module from Hydrophilic and Hydrophobic Surfaces
نویسندگان
چکیده
منابع مشابه
Fibronectin Adsorption on Hydrophilic and Hydrophobic Surfaces
Studies have been carried out on the adsorption properties of plasma fibronectin (FN) on hydrophobic and hydrophilic surfaces. The hydrophobic and hydrophilic surfaces used were nonwettable bacteriological dishes and wettable tissue culture dishes, respectively. At low plasma FN concentrations, there was more plasma FN binding to hydrophobic surfaces than to hydrophilic surfaces. Under these co...
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Domain 10 of type III fibronectin (10FNIII) is known to play a pivotal role in the mechanical interactions between cell surface integrins and the extracellular matrix. Recent molecular dynamics simulations have predicted that 10FNIII, when exposed to a stretching force, unfolds along two pathways, each with a distinct, mechanically stable intermediate. Here, we use single-molecule force spectro...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2011
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2010.12.2816