MECCSIM, training software for micellar electrokinetic capillary chromatography

Analysis of prostaglandins by micellar electrokinetic capillary chromatography.

This paper presents a rapid and reliable micellar electrokinetic capillary chromatography (MEKC) method to separate major prostaglandins and thromboxane B2. The running buffer was modified with sodium dodecyl sulfate (SDS). The effects of the SDS concentration on the migration behavior of analytes was also examined. Moreover, the influences of electrolyte concentration and capillary temperature...

Micellar electrokinetic chromatography.

Principles of micellar electrokinetic capillary chromatography applied in pharmaceutical analysis.

Since its introduction capillary electrophoresis has shown great potential in areas where electrophoretic techniques have rarely been used before, including here the analysis of pharmaceutical substances. The large majority of pharmaceutical substances are neutral from electrophoretic point of view, consequently separations by the classic capillary zone electrophoresis; where separation is base...

Retention indices in micellar electrokinetic chromatography

The use o f retent ion indices in mice l la r electrokinet ic ch roma tog raphy ( M E K C ) is eva lua ted both f rom a theoretical and a practical point o f view. F undamen t a l equa t ions for the de te rmina t ion o f retent ion indices in M E K C are descr ibed, showing that re tent ion indices are independen t o f the surfac tant concentra t ion. Possibi l i t ies as well as l imita t ion...

Twenty-five years of micellar electrokinetic chromatography

Micellar electrokinetic chromatography (MEKC), which can separate neutral analytes as well as charged analytes by the capillary electrophoretic technique, was developed in 1982 and the first paper was published in 1984. The authors’ group concentrated their effort into the characterization of MEKC as a separation technique until early 1990s. Most issues in MEKC separations were successfully sol...