Measurement of renal tissue oxygenation with blood oxygen level-dependent MRI and oxygen transit modeling

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Measurement of renal tissue oxygenation with blood oxygen level-dependent MRI and oxygen transit modeling.

Blood oxygen level-dependent (BOLD) MRI data of kidney, while indicative of tissue oxygenation level (Po2), is in fact influenced by multiple confounding factors, such as R2, perfusion, oxygen permeability, and hematocrit. We aim to explore the feasibility of extracting tissue Po2 from renal BOLD data. A method of two steps was proposed: first, a Monte Carlo simulation to estimate blood oxygen ...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Renal Physiology

سال: 2014

ISSN: 1931-857X,1522-1466

DOI: 10.1152/ajprenal.00575.2013