Mean Corpuscular Volume (MCV) and Mean Corpuscular Hemoglobin (MCH) Determinations in Newborns with Beta Thalassemia
نویسندگان
چکیده
منابع مشابه
Thalassemia and Hemoglobinopathy Despite Normal Level of Hemoglobin Concentration and Normal Mean Corpuscular Volume
The small mean corpuscular volume (MCV) of red blood cell is one of the indicators for thalassemia and hemoglobinopathy screening. As other screening methods, it may have some degrees of limitation. The retrospective study was performed among 104 patients who had various kinds of thalassemia or hemoglobinopathy despite having normal hemoglobin (Hb) concentration and normal mean corpuscular volu...
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The relationship between the degree of microcytosis and the type of mutation carried by beta-thalassemia heterozygotes was investigated. In 113 individuals, 18 different mutations were identified, correlated with mean corpuscular volume (MCV) values, and analyzed statistically. Overall, there was a wide range of MCV (56.3-87.3 fL). In almost all cases, carriers of beta(0) mutations had an MCV b...
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The mean corpuscular volume (MCV) of blood after storage for up to 24 days under various temperature conditions in ethylene diamine tetracetic acid, acid citrate dextrose, citrate phosphate dextrose, and Alsever's solution was measured using the Coulter S. Storage of blood overnight at 23 degrees centigrade increased the MCV, while there was no significant change after similar storage at 4 degr...
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A very high glucose level in a diabetic was associated with an increased electronic mean corpuscular volume (MCV). The hematocrit was falsely high and the mean corpuscular hemoglobin concentration (MCHC) falsely low, while the mean corpuscular hemoglobin (MCH) was normal. Blood smears failed to corroborate the abdominal indices. Correct values could be obtained by predilution of the blood in is...
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An abnormal and transient increase of the Coulter mean red cell volume (MCV) was observed in four of 10 patients with diabetic decompensation. A sequential study of haematological and biochemical measurements in these patients revealed that this phenomenon was associated with the hyperosmolar state. The proposed mechanism and the clinical implications of this change are briefly discussed.
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ژورنال
عنوان ژورنال: Blood
سال: 2018
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2018-99-110991