Maturation pathway of metalloprotease produced by Aeromonas sobria
نویسندگان
چکیده
منابع مشابه
Aerolysin is activated by metalloprotease in Aeromonas veronii biovar sobria.
Aeromonas veronii is an opportunistic human pathogen that causes diarrhoea and extraintestinal infections, such as wound infection and septicaemia. An A. veronii protease (AVP) from a biovar sobria strain, AeG1, was partially purified and characterized. Mature AVP hydrolysed casein but not elastin, and protease activity was inhibited by metalloprotease inhibitors. Nucleotide sequence analysis s...
متن کاملPurification and characterization of cytolytic toxins produced by Aeromonas hydrophila and Aeromonas veronii biotype sobria strains.
Cytolytic toxins produced by Aeromonas hydrophila and Aeromonas veronii biotype sobria strains were partially purified from culture filtrates by two steps of purification: ammonium sulfate precipitation and hydrophobic chromatography using Phenyl-Sepharose CL-4B. Hemolytic activity was detected in one or two peaks in elution profile. Purified toxins were also cytotoxic to Vero and CHO cells. Mo...
متن کاملSkin and soft-tissue infections caused by Aeromonas sobria.
No (%) of patients (n = 22) Age, years 56.8 ± 18.6 Age 65 years, n (%) 8 (36.4) Female, n (%) 5 (22.7) Underlying condition Active cancer 3 (13.6) Diabetes mellitus 2 (9.1) Liver cirrhosis 2 (9.1) End-stage renal disease 1 (4.5) Receiving immunosuppressant drugs 1 (4.5) Water exposure 7 (31.8) Trauma 14 (63.6) Necrotizing fasciitis 2 (9.1) Laboratory findings White blood cell (cell/uL) 11,227.8...
متن کاملMortality of therapeutic fish Garra rufa caused by Aeromonas sobria.
OBJECTIVE To investigate a case of mass mortality of Garra rufa (G. rufa) from a fish hatchery farm in Slovakia. METHODS Causative bacterial agent was swabbing out of affected fish skin area and subsequently identified using commercial test system. Antibiotic susceptibility was determined by the disk diffusion method. RESULTS Infected G. rufa was characterized by abnormal swimming behaviour...
متن کاملFulminant necrotizing fasciitis caused by Aeromonas sobria in neutropenic patients.
Infection with Aeromonas species has been reported to occur in neutropenic patients. Necrotizing fasciitis caused by Aeromonas species is uncommon but potentially life-threatening. We herein describe three cases of fulminant necrotizing fasciitis caused by Aeromonas sobria in neutropenic patients. These cases shared many clinical characteristics, including shock, coagulopathy, multiple organ fa...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 2010
ISSN: 0385-5600,1348-0421
DOI: 10.1111/j.1348-0421.2010.00258.x