Masters of change

Masters change, slaves remain.

Sex determination offers an opportunity to address many classic questions of developmental biology. In addition, because sex determination evolves rapidly, it offers an opportunity to investigate the evolution of genetic hierarchies. Sex determination in Drosophila melanogaster is controlled by the master regulatory gene, Sex lethal (Sxl). DmSxl controls the alternative splicing of a downstream...

Schirmer Middle Managers - Masters of Change Politics

Towards a different view of middle managers and their roles in strategic decentralisation processes-(7350 words) Summary Middle managers have often been blamed for being inflexible status quo defenders in organisational change processes. However, research results reported in this paper, drawn from in-depth case studies of company restructuring in Germany during the nineties, suggests that middl...

Route masters

Many turtle species are endangered through a variety of human activities, from beach development, boating and shipping, and fishing. Awareness of the problems has mostly focused on protection of beaches used for breeding as individuals return to highly specific sites where they are particularly vulnerable. Apart from their breeding sites, much less is known about their long and complex movement...

British Masters of Medicine

Mitochondria: Masters of Epigenetics

Accumulating evidence argues that aging exerts a profound influence on epigenetics, and vice versa. A pair of studies by Merkwirth et al. and Tian et al. now provide insights on how mitochondrial stress experienced by C. elegans larvae propagates a specific and persistent epigenetic response that protects adult cells and extends lifespan.