Mast cells in leprosy skin lesions

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Langerhans Cells in Skin Lesions of Leprosy

Background: Langerhans cells are important in the pathogenesis of leprosy.  A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...

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Mast cells in leprosy skin lesions.

The density and distribution of mast cells was assessed in skin biopsies of 118 untreated leprosy cases and 20 healthy individuals taken as controls. Mast cells were present in only small numbers in the skin biopsies of healthy individuals. Significantly higher mast cell counts were obtained in the skin lesions of indeterminate leprosy (P < 0.01). The mast cell count in the tuberculoid group wa...

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langerhans cells in skin lesions of leprosy

background: langerhans cells are important in the pathogenesis of leprosy.  a recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions.   objective: to investigate a possible relationship between the number of langerhans cells and the histopathologic spectrum of lesions in patients with leprosy.   methods: an immunohistochemical staining for s100 ...

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Histopathology of skin lesions in leprosy.

INTRODUCTION Histopathological examination of skin or nerve biopsies or the demonstration of lepra bacilli in skin smears are the only laboratory means of confirming a diagnosis of leprosy.' The histological features are particularly useful in the early stages when there i s a sparsity of bacilli in skin smears. The histological changes in the skin in leprosy are p r ~ t e a n , ~ ~ and it is e...

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The Skin Lesions of Neural Leprosy

The present report concerns an extension, to patients of the Indian race, of the study of the leprides that has been dealt with in the preceding articles of this series. Besides the original objective of determining conclusively the essential nature of such lesions, the purpose has been to contribute if possible to an understanding of variations of the disease in different races. To that end th...

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ژورنال

عنوان ژورنال: Leprosy Review

سال: 2001

ISSN: 0305-7518

DOI: 10.5935/0305-7518.20010006