Mass spectral studies of probe pyrolysis products of intact oligoribonucleotides

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Mass spectral studies of probe pyrolysis products of intact oligoribonucleotides.

Pyrolysis of underivatized homogeneous oligoribonucleotides in the source of a mass spectrometer leads to production of simple mass spectra which resemble the spectra of the bases themselves. It is proposed that pyrolysis occurs by hydrogen transfer to the base moiety followed by elimination of the neutral base. Ionization by electron impact gives rise to the observed spectra. Mixed oligoribonu...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 1978

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/5.8.2695