Mass Antibiotic Treatment Alone Does Not Eliminate Ocular Chlamydial Infection
نویسندگان
چکیده
منابع مشابه
Mass Antibiotic Treatment Alone Does Not Eliminate Ocular Chlamydial Infection
Trachoma is caused by Chlamydia trachomatis and is the leading infectious cause of preventable blindness globally. For trachoma control, the World Health Organization (WHO) promotes the SAFE strategy, an integrated program of 1) eyelid Surgery to correct the in-turned eyelashes associated with severe trachoma and stops pain and minimizes risk of corneal damage; 2) Antibiotic treatment for activ...
متن کاملThe Relationship between Active Trachoma and Ocular Chlamydia trachomatis Infection before and after Mass Antibiotic Treatment
BACKGROUND Trachoma is a blinding disease, initiated in early childhood by repeated conjunctival infection with the obligate intracellular bacterium Chlamydia trachomatis. The population prevalence of the clinical signs of active trachoma; ''follicular conjunctivitis" (TF) and/or ''intense papillary inflammation" (TI), guide programmatic decisions regarding the initiation and cessation of mass ...
متن کاملExperimentally induced ocular chlamydial infection in infant pig-tailed macaques.
Four Macaca nemestrina monkeys were inoculated in the conjunctiva with Chlamydia trachomatis (strain E) at 6 weeks of age. A fifth monkey was inoculated with HeLa cell materials only. Ten weeks later, all monkeys were reinoculated with either strain E or strain C. All inoculated monkeys were susceptible to infection with C. trachomatis as documented by fluorescent antibody staining of smears an...
متن کاملOcular chlamydial infection in a university eye clinic.
In the University Hospital, Kuala Lumpur, from 1984 to 1990, 184 patients with acute conjunctivitis were examined for chlamydial infection by direct immunofluorescence. Overall, 52 (28.3%) were found to be positive for chlamydial antigen. There was no significant difference in the detection rate between men and women and among the 3 major ethnic groups. The detection rate was highest among sexu...
متن کاملTrachoma and Ocular Chlamydial Infection in the Era of Genomics
Trachoma is a blinding disease usually caused by infection with Chlamydia trachomatis (Ct) serovars A, B, and C in the upper tarsal conjunctiva. Individuals in endemic regions are repeatedly infected with Ct throughout childhood. A proportion of individuals experience prolonged or severe inflammatory episodes that are known to be significant risk factors for ocular scarring in later life. Conti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS Neglected Tropical Diseases
سال: 2009
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0000394