منابع مشابه
Molecular and functional aspects of parasite invasion.
Apicomplexan parasites have evolved an efficient mechanism to gain entry into non-phagocytic cells, hence challenging their hosts by the establishment of infection in immuno-privileged tissues. Gliding motility is a prerequisite for the invasive stage of most apicomplexans, allowing them to migrate across tissues, and actively invade and egress host cells. In the late 1960s, detailed morphologi...
متن کاملSelf-targeting blocks malaria parasite invasion
1140 INSIGHTS | The Journal of Experimental Medicine Reticular dysgenesis (RD) is the most severe form of human severe combined immunodeficiency (SCID). It is associated with mutations in adenylate kinase 2 (AK2), the mitochondrial intermembrane space enzyme that regulates energy metabolism by reversibly catalyzing the reaction of ATP with AMP to generate two molecules of ADP. However, the impa...
متن کاملBiological invasions and host-parasite coevolution: different coevolutionary trajectories along separate parasite invasion fronts.
Host-parasite coevolution has rarely been observed in natural systems. Its study often relies on microparasitic infections introducing a potential bias in the estimation of the evolutionary change of host and parasite traits. Using biological invasions as a tool to study host-parasite coevolution in nature can overcome these biases. We demonstrate this with a cross-infection experiment in the i...
متن کاملReassessing the mechanics of parasite motility and host-cell invasion
507 The Rockefeller University Press $30.00 J. Cell Biol. Vol. 214 No. 5 507–515 www.jcb.org/cgi/doi/10.1083/jcb.201605100 Introduction The ancient phylum Apicomplexa includes many of the world’s preeminent pathogens (Woo et al., 2015), such as Plasmodium, the genus responsible for more than half a million malaria-related deaths each year (White et al., 2014), and Toxoplasma gondii, one of the ...
متن کاملBlocking malaria parasite invasion of mosquito salivary glands.
Release of genetically engineered mosquitoes resistant to parasite infections has been proposed as a novel way to control malaria transmission, and several important advances have been made in anticipation of testing this approach. In particular, the development of synthetic effector genes that block parasite development in mosquito hosts has exploited a number of different mechanisms that resu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Trends in Parasitology
سال: 2008
ISSN: 1471-4922
DOI: 10.1016/j.pt.2007.10.008