Markers of Nonselective and Specific NK Cell Activation

Activation Markers of Nonselective and Specific NK Cell

Expression of CK8 and CK17, Specific Epithelial Markers, by Oral Squamous Cell Carcinoma Cell Lines

Objectives Oral squamous cell carcinoma (OSCC) is among the most common cancers worldwide. This study aimed to assess the expression of CK8 and CK17 by OSCC cell lines in Iranian patients. Methods This observational study was conducted on three OSCC cell lines with a minimum of 45 passages. Cells isolated from three patients with OSCC were cultured and passaged. Expression of CK8 and CK17 epi...

[Measurement of NK cell and macrophage activation].

FcgammaRIII(CD16), one of the low-affinity IgG Fc receptors exists in two forms. FcgammaRIIIa is expressed on NK cells, a subset of T lymphocytes, a subpopulation of monocytes and macrophages, and shows a cell type specific glycosylation pattern. FcgammaRIIIb is expressed exclusively on neutrophils in two allotypes, NA1/2, and it can be induced on eosinophils. Both FcyRIIIs are released from th...

Specific subdomains of Vav differentially affect T cell and NK cell activation.

The Vav protooncogene is a multidomain protein involved in the regulation of IL-2 gene transcription in T cells and the development of cell-mediated killing by cytotoxic lymphocytes. We have investigated the differential roles that specific protein subdomains within the Vav protooncogene have in the development of these two distinct cellular processes. Interestingly, a calponin homology (CH) do...

APC-independent NK cell activation.