Mapping Alzheimer's disease progression in 1309 MRI scans: Power estimates for different inter-scan intervals

Mapping Alzheimer's disease progression in 1309 MRI scans: Power estimates for different inter-scan intervals

Neuroimaging centers and pharmaceutical companies are working together to evaluate treatments that might slow the progression of Alzheimer's disease (AD), a common but devastating late-life neuropathology. Recently, automated brain mapping methods, such as tensor-based morphometry (TBM) of structural MRI, have outperformed cognitive measures in their precision and power to track disease progres...

Segmentation of Alzheimers Disease in PET scan datasets using MATLAB

Positron Emission Tomography (PET) scan images are one of the bio medical imaging techniques similar to that of MRI scan images but PET scan images are helpful in finding the development of tumors. The PET scan images requires expertise in the segmentation where clustering plays an important role in the automation process. The segmentation of such images is manual to automate the process cluste...

Automated Planning of Scan Geometries in Spine MRI Scans

Consistency of MR scan planning is very important for diagnosis, especially in multi-site trials and follow-up studies, where disease progress or response to treatment is evaluated. Accurate manual scan planning is tedious and requires skillful operators. On the other hand, automated scan planning is difficult due to relatively low quality of survey images ("scouts") and strict processing time ...

Rab11 in Disease Progression

Membrane/ protein trafficking in the secretory/ biosynthetic and endocytic pathways is mediated by vesicles. Vesicle trafficking in eukaryotes is regulated by a class of small monomeric GTPases the Rab protein family. Rab proteins represent the largest branch of the Ras superfamily GTPases, and have been concerned in a variety of intracellular vesicle trafficking and different intracellular sig...

Image Registration of Lung CT Scans for Monitoring Disease Progression