MAPK/P53-mediated FASN expression in bone tumors

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MAPK/P53-mediated FASN expression in bone tumors

The correlation between mitogen-activated protein kinase (MAPK)/P53 signaling-dependent fatty acid synthase (FASN) expression and bone tumors was examined in the present study. We established the SH081 bone tumor cell line, which was used to determine the expression of FASN and MAPK/P53 at the mRNA and protein levels in bone tumor cells and normal cells. Compared with the normal cells, the expr...

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ژورنال

عنوان ژورنال: Oncology Letters

سال: 2017

ISSN: 1792-1074,1792-1082

DOI: 10.3892/ol.2017.6015