منابع مشابه
NICE backs leukaemia drug after manufacturer drops price.
The National Institute for Health and Clinical Excellence has recommended nilotinib (Tasigna) for the firstline treatment of chronic myeloid leukaemia after the manufacturer agreed to reduce the price for the NHS. In final draft guidance NICE also reaffirmed the use of imatinib (Glivec) for firstline treatment of the rare condition that affects around 560 people in the UK each year. Both drugs ...
متن کاملPKC Defends Crown Against Munc13
Protein kinase C has long been thought to mediate DAG signaling at the synapse. Recently PKC has been supplanted by members of the Unc13 family as the predominant effectors of DAG signaling. Thanks to a study by Wierda and colleagues in this issue of Neuron, PKC returns to reclaim part of the kingdom: both pathways must be active to activate presynaptic potentiation.
متن کاملAndrea Bajo Defends his Ph.D. Dissertation
Andrea Bajo successfully defended his Ph.D. dissertation on 3/15/2013. His dissertation titled " Control, Sensing, and Telemanipulation of Surgical Continuum Robots" presents contributions in the areas of contact detection and estimation of contact location for continuum robots, hybrid force/motion control for continuum robots, and constrained telemanipulation of continuum robots. Algorithms de...
متن کاملHeparin defends against the toxicity of circulating histones in sepsis.
Although circulating histones were demonstrated as major mediators of death in septic mice models, their roles in septic patients are not clarified. The present study sought to evaluate the clinical relevance of the circulating histone levels in septic children, and the antagonizing effects of heparin on circulating histones. Histone levels in the plasma of septic children were significantly hi...
متن کاملHuman CRP defends against the toxicity of circulating histones.
C-reactive protein (CRP) is an acute-phase protein that plays an important defensive role in innate immunity against bacterial infection, but it is also upregulated in many noninfectious diseases. The generic function of this highly conserved molecule in diseases that range from infection, inflammation, trauma, and malignancy is not well understood. In this article, we demonstrate that CRP defe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 1996
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.313.7067.1263a