Manipulation of a Micro-Object Using Topological Hydrodynamic Tweezers

A microgripper using piezoelectric actuation for micro-object manipulation

Design, fabrication and tests of a monolithic compliant-flexure-based microgripper were performed. The geometry design and the material tresses were considered through the finite element analysis. The simulation model was used to study in detail profiles of von Mises stresses nd deformation. The maximum stress in the microgripper is much smaller than the critical stress values for fatigue. The ...

Multiplying optical tweezers force using a micro-lever.

This study presents a photo-driven micro-lever fabricated to multiply optical forces using the two-photon polymerization 3D-microfabrication technique. The micro-lever is a second class lever comprising an optical trapping sphere, a beam, and a pivot. A micro-spring is placed between the short and long arms to characterize the induced force. This design enables precise manipulation of the micro...

Independent trapping and manipulation of microparticles using dexterous acoustic tweezers

Optically-controlled manipulation of live cells using optoelectronic tweezers

Optoelectronic tweezers (OET) provides a non-invasive, low-power, optical manipulation tool for trapping, transporting, and separating microparticles, cells, and other bioparticles. The OET device uses a photosensitive layer to form "virtual electrodes" upon exposure to light, creating non-uniformities in an applied electric field. The electric field gives rise to a force known as dielectrophor...

Microcrystal manipulation with laser tweezers

X-ray crystallography is the method of choice to deduce atomic resolution structural information from macromolecules. In recent years, significant investments in structural genomics initiatives have been undertaken to automate all steps in X-ray crystallography from protein expression to structure solution. Robotic systems are widely used to prepare crystallization screens and change samples on...