منابع مشابه
Biomarkers of manganese intoxication.
Manganese (Mn), upon absorption, is primarily sequestered in tissue and intracellular compartments. For this reason, blood Mn concentration does not always accurately reflect Mn concentration in the targeted tissue, particularly in the brain. The discrepancy between Mn concentrations in tissue or intracellular components means that blood Mn is a poor biomarker of Mn exposure or toxicity under m...
متن کاملParkinsonism induced by chronic manganese intoxication--an experience in Taiwan.
Excessive manganese exposure may induce a neurological syndrome called manganism, which is similar to Parkinson's disease (PD). However, close observation of patients with manganism reveals a clinical disease entity different from PD, not only in the clinical manifestations, but also in therapeutic responses, in neuroimaging studies such as magnetic resonance imaging, positron emission tomograp...
متن کاملChelation therapy of manganese intoxication with para-aminosalicylic acid (PAS) in Sprague-Dawley rats.
Para-aminosalicylic acid (PAS), an FDA-approved anti-tuberculosis drug, has been used successfully in the treatment of severe manganese (Mn)-induced Parkinsonism in humans [Jiang Y-M, Mo X-A, Du FQ, Fu X, Zhu X-Y, Gao H-Y, et al. Effective treatment of manganese-induced occupational Parkinsonism with p-aminosalicylic acid: a case of 17-year follow-up study. J Occup Environ Med 2006;48:644-9]. T...
متن کامل385 Parkinsonism Induced by Chronic Manganese Intoxication – An Experience in Taiwan
402 Isolation and Differentiation of Human Mesenchymal Stem Cells Obtained from Second Trimester Amniotic Fluid; Experiments at Chang Gung Memorial Hospital Hsiu-Huei Peng, MD; Tzu-Hao Wang, MD, PhD; An-Shine Chao, MD; Shuenn-Dyh Chang, MD 408 Associations between Brain-derived Neurotrophic Factor G196A Gene Polymorphism and Clinical Phenotypes in Schizophrenia Patients Tiao-Lai Huang, MD; Chie...
متن کامل[Chronic manganese intoxication due to methcathinone (ephedron) abuse: a case report].
Known as an occupational disease, chronic manganese intoxication is recently being observed among abusers of psychoactive substances. Methcathinone hydrochloride is obtained by combining ephedrine/pseudoephedrine and potassium permanganate. Various neuropsychiatric symptoms have been reported among Efedron users. Our patient is a 29 year old male, who was referred to our hospital from a state g...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1949
ISSN: 0035-9157
DOI: 10.1177/003591574904200209