Management of Operative Harvest for Bone Marrow Donors
نویسندگان
چکیده
منابع مشابه
How to harvest bone marrow for transplantation
Introduction Over the past decade bone marrow transplantation (BMT) has graduated from being an experimental treatment to having an established role in the first line management of patients with life threatening haematological disorders. The therapeutic principle involved is that the administration of myelotoxic treatment (preparative protocol), at doses beyond the threshold normally set to gua...
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To determine the feasibility of obtaining bone marrow cells from cadaver donors for transplantation, marrow cells were prepared from 17 cadaver donors. After surgical removal of the iliac crest, as many as 2 X 10(9) cells were isolated. Cadaver marrow had a lower percentage of T cells (mean of 10%) than did marrow from living donors. The T cells were lysed by a monoclonal antibody and human com...
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Approximately 1 in 20 unrelated donors are asked to make a second donation of hematopoietic progenitor cells, the majority for the same patient. Anthony Nolan undertook a study of subsequent hematopoietic progenitor cell donations made by its donors from 2005 to 2011, with the aims of predicting those donors more likely to be called for a second donation, assessing rates of serious adverse reac...
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Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...
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PURPOSE/OBJECTIVES To review literature regarding children as bone marrow donors and describe the evaluation of an individualized intervention to support children who will be donors for parents or siblings. DATA SOURCE Research studies, abstracts, and clinical reports describing interventions or psychosocial issues related to child donors, parent interviews, and clinical experiences. DATA S...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2014
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2013.12.537