Management of Hereditary Breast Cancer

Management of Hereditary Breast Cancer

D.M. Eccles, P. Simmonds, J. Goddard, M. Coultas, F. Lalloo, G. Evans and N. Haites in collaboration with the European Familial Breast Cancer Collaborative Group Department of Clinical Genetics, Princess Ann Hospital, Coxford Road, Southampton, UK Medical Oncology, Royal South Hants Hospital, Southampton, UK Medical Statistics and Computing, Southampton General Hospital, Southampton, UK Clinica...

Hereditary Breast-Ovarian Cancer

Prophylaxis of hereditary breast cancer

Hereditary breast and ovarian cancer

Familial breast cancer was first recognized in the Roman medical literature of 100 AD [1]. The first documentation of familial clustering of breast cancer in modern times was published by Broca, who reported 10 cases of breast cancer in 4 generations of his wife’s family [2]. In the middle of the nineteen nineties it was proven at the molecular level that a substantial number of breast and ovar...

Breast Cancer: Risk Factors, Diagnosis and Management

ABSTRACT           Breast cancer remains the most common cancer of women and one of the most common causes of cancer-related deaths worldwide. In spite of major advances in breast cancer diagnosis and treatment, the incidence of breast cancer remains high and the treatment of metastatic breast cancer remains challenging. This review presents an over...