Mammary intraepithelial neoplasia outgrowths (MINO): MINO and human ductal carcinoma in situ
نویسندگان
چکیده
منابع مشابه
Mino 18_08
Cancer found in the post-operative remnant stomach includes both newly developed cancer after surgery for benigndisease (PRC) and metachronous multiple cancer (MRC). Differences in the carcinogenic pathway between PRC and MRC have been suspected from clinical studies. However, no study has demonstrated the difference in molecular alteration between these diseases. P16 is inactivated predominant...
متن کاملMINO —System Integration
This paper presents the integration of MINO — a toolkit for rapid application development of graphical user interfaces (GUI RAD) in Forth— into the system. Two main areas of interrest are data base query via SQL and integration of OpenGL. Other improvements of MINO are also covered. This text blatantly contains parts that were already presented last time and on the last Forth Tagung in Moers.
متن کاملPolyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomes.
The development of models to investigate the pathobiology of premalignant breast lesions is a critical prerequisite for development of breast cancer prevention and early intervention strategies. Using tissue transplantation techniques, we modified the widely used polyomavirus middle T (PyV-mT) transgenic mouse model of breast cancer to study the premalignant stages of tumorigenesis. Premalignan...
متن کاملDuctal carcinoma in situ arising in mammary hamartoma.
Hamartoma of the breast is an uncommon lesion. Although it can possess characteristic radiological features, the pathological appearance is not distinctive. Hamartoma is generally considered benign, but four cases have been reported with ductal and lobular carcinoma arising in hamartomas. This report describes further cases of hamartoma from which ductal carcinoma in situ arose, with one showin...
متن کاملGlucose Uptake and Intracellular pH in a Mouse Model of Ductal Carcinoma In situ (DCIS) Suggests Metabolic Heterogeneity
Mechanisms for the progression of ductal carcinoma in situ (DCIS) to invasive breast carcinoma remain unclear. Previously we showed that the transition to invasiveness in the mammary intraepithelial neoplastic outgrowth (MINO) model of DCIS does not correlate with its serial acquisition of genetic mutations. We hypothesized instead that progression to invasiveness depends on a change in the mic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Breast Cancer Research
سال: 2003
ISSN: 1465-542X
DOI: 10.1186/bcr704