Maltodextrin: A Novel Excipient Used in Sugar-Based Orally Disintegrating Tablets and Phase Transition Process
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چکیده
منابع مشابه
Evidence-Based Nanoscopic and Molecular Framework for Excipient Functionality in Compressed Orally Disintegrating Tablets
The work investigates the adhesive/cohesive molecular and physical interactions together with nanoscopic features of commonly used orally disintegrating tablet (ODT) excipients microcrystalline cellulose (MCC) and D-mannitol. This helps to elucidate the underlying physico-chemical and mechanical mechanisms responsible for powder densification and optimum product functionality. Atomic force micr...
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Orally disintegrating tablets (ODTs), also known as fast melts, quick melts, fast disintegrating and orodispersible systems, have the unique property of disintegrating in the mouth in seconds without chewing and the need of water and are thus assumed to improve patient compliance. Conventional methods like direct compression, wet granulation, moulding, spray-drying, freeze-drying and sublimatio...
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---------------------------------------------------RECENT MAJOR CHANGES------------------------------------------------- Indications and Usage, Schizophrenia/Adolescents (1.1) 08/2007 Indications and Usage, Bipolar Mania/Pediatrics (1.2) 08/2007 Dosage and Administration, Schizophrenia/Adolescents (2.1) 08/2007 Dosage and Administration, Bipolar Mania/Pediatrics (2.2) 08/2007 -----------------...
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Article history: Received on: 06/01/2014 Revised on: 22/01/2014 Accepted on: 12/02/2014 Available online: 27/02/2014 Orally disintegrating tablets (ODTs) have greatly increased dosage forms which have remarkable impact on the patient compliance especially for the pediatric, geriatric and psychiatric patients with deglutition disorders. Several technologies either conventional or patented based ...
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Its empirical formula is C15H19N5•C7H6O2, representing a molecular weight of the free base of 269.4. Rizatriptan benzoate is a white to off-white, crystalline solid that is soluble in water at about 42 mg per mL (expressed as free base) at 25°C. MAXALT Tablets and MAXALT-MLT* Orally Disintegrating Tablets are available for oral administration in strengths of 5 and 10 mg (corresponding to 7.265 ...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2010
ISSN: 1530-9932
DOI: 10.1208/s12249-010-9423-y