Malignant psammomatous melanotic schwannoma of the spine: A component of Carney complex
نویسندگان
چکیده
منابع مشابه
Psammomatous Melanotic Schwannoma: A Challenging Histological Diagnosis
Psammomatous melanotic schwannoma (PMS) is a rare pigmented tumor that can be part of the Carney complex. Here, we describe the case of a 35-year-old female patient presenting an isolated subcutaneous PMS. Histopathological analysis could not formally exclude the malignant nature of the tumor. The challenging histological diagnosis and consequently the management of the patient are described.
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Psammomatous melanotic schwannoma is a rare form of schwannoma that is distinct in terms of presentation, location, and nature compared to other types. This tumor is highly associated with Carney complex, but has also been seen in the neurofibromatosis syndromes. Although discovered over 80 years ago, official management guidelines have not been established. The following review comprises the c...
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A case of malignant melanotic schwannoma arising in the right upper lobe bronchus of a 27 year old man is presented. Tumours of this type most commonly occur in spinal nerve roots and are generally considered to be benign. The behaviour of those originating elsewhere is less predictable. As far as we are aware this is the first reported case affecting the respiratory tract.
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Known germline gene abnormalities cause one-fifth of the pituitary adenomas in children and adolescents, but, in contrast with other pituitary tumor types, the genetic causes of corticotropinomas are largely unknown. In this study, we report a case of Cushing disease (CD) due to a loss-of-function mutation in PRKAR1A, providing evidence for association of this gene with a corticotropinoma. A 15...
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We present a case of an intramedullary melanotic schwannoma (IMS) of the thoracic spinal cord. To our knowledge, this is the seventh reported case of an IMS of the central nervous system. Schwannomas are benign nerve sheath tumors of neural crest origin composed entirely of well differentiated Schwann cells that typically occur in peripheral nerves. Both the intramedullary location and the mela...
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ژورنال
عنوان ژورنال: Surgical Neurology International
سال: 2011
ISSN: 2152-7806
DOI: 10.4103/2152-7806.85609