Malignant pleural mesothelioma with osteosarcomatous differentiation: characteristic bone scintigraphy findings associated with enhanced tumorous osteogenesis☆
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چکیده
منابع مشابه
Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma
Malignant pleural mesothelioma (mesothelioma) is a highly aggressive cancer without an effective treatment. Cul4A, a scaffold protein that recruits substrates for degradation, is amplified in several human cancers, including mesothelioma. We have recently shown that Cul4A plays an oncogenic role in vitro and in a mouse model. In this study, we analysed clinical mesothelioma tumours and found mo...
متن کاملCD26 overexpression is associated with prolonged survival and enhanced chemosensitivity in malignant pleural mesothelioma.
PURPOSE Malignant pleural mesothelioma (MPM) is an aggressive and therapy-resistant neoplasm arising from the pleural mesothelial cells, without established indicators to predict responsiveness to chemotherapy. EXPERIMENTAL DESIGN Our study involving 79 MPM patients showed that 73.4% of MPM expressed CD26 on cell membrane. RESULTS The majority of epithelioid and biphasic types of MPM expres...
متن کاملLocalized malignant pleural mesothelioma with renal metastasis
Localized malignant pleural mesothelioma (LMM) is a rare subset of malignant pleural mesothelioma. Its epidemiology, biology, natural history and optimal treatment are poorly understood. We report a case of LMM treated aggressively with complete surgical resection and adjuvant radiotherapy, but subsequently complicated by local chest wall recurrence and solitary metastasis to the kidney. This c...
متن کامل[Malignant pleural mesothelioma].
Overview Mesothelioma is a rare cancer that is estimated to occur in approximately 2500 people in the United States every year.1,2 These NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) focus on malignant pleural mesothelioma (MPM), which is the most common type; mesothelioma can also occur in other sites (e.g., peritoneum, pericardium, tunica vaginalis testis). The disease is di...
متن کاملMalignant phyllodes tumour as an intracystic growth with osteosarcomatous differentiation.
Phyllodes tumour is an uncommon fibro epithelial tumour of breast that often presents clinically as a rapidly enlarging lump. On mammography it appears as a soft tissue density well circumscribed mass. Ultrasound shows it to be a solid hypoechoic mass with small cystic spaces. A case of malignant phyllodes tumour with an atypical appearance of intracystic tumour on sonography is reported with p...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 2011
ISSN: 1010-7940
DOI: 10.1016/j.ejcts.2010.06.008