منابع مشابه
Screening of nerve agent degradation products by MALDI-TOFMS.
A novel method for the rapid screening of degradation products derived from nerve agents by matrix-assisted laser desorption ionization time-of-flight mass spectrometry is described. Five standard products were selected as model compounds, including isopropyl methylphosphonic acid (IMPA), pinacolyl methylphosphonic acid (PMPA), ethyl methylphosphonic acid (EMPA), isobutyl methylphosphonic acid ...
متن کاملDevelopment of a multi-frequency laser for use in MALDI-TOFMS.
The application of a multi-frequency laser source for the use in matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOFMS) is described. An elliptically polarized beam of a Nd:YAG laser emitting at 355 nm (200 mJ) is focused into a Raman shifter, filled with high pressure hydrogen. As a result, numerous Raman lasers (including vibrational and rotational Raman em...
متن کاملMethod for estimating the isotopic distributions of metabolically labeled proteins by MALDI-TOFMS: application to NMR samples.
We have developed an efficient method of estimating metabolic incorporation of heavy isotopes into proteins, including those where a single amino acid carries the label. The protein is digested with trypsin, and the resulting peptide mixture is examined directly by MALDI-TOF mass spectrometry. Peptides are chosen for analysis if they contain one or more labeled atoms and also exhibit clearly se...
متن کاملNovel circulating peptide biomarkers for esophageal squamous cell carcinoma revealed by a magnetic bead-based MALDI-TOFMS assay
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant neoplasms worldwide. Patients are often diagnosed at advanced stages with poor prognosis due to the absence of obvious early symptoms. Here, we applied a high-throughput serum peptidome analysis to identify circulating peptide markers of ESCC. Weak cationic exchange magnetic beads coupled to matrix-assisted laser deso...
متن کاملDevelopment of spray deposition/MALDI-TOFMS and its application to the rapid screening of hydrolysis products derived from nitrogen mustards.
A novel method for preparing samples for use in MALDI-TOFMS (matrix-assisted laser desorption ionization time-of-flight mass spectrometry) is described. Seven hydrolysis products derived from nitrogen mustards and CHCA (alpha-cyano-4-hydroxycinnamic acid) were selected as model compounds and the matrix, respectively. A capillary atomizer was used for evaporative and spray deposition of the samp...
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ژورنال
عنوان ژورنال: Journal of the Japan Society of Colour Material
سال: 2006
ISSN: 0010-180X
DOI: 10.4011/shikizai1937.79.257