Making it personal: a biography of connections

Making it personal: translational bioinformatics

One of the most exciting research areas in Translational Bioinformatics 2 is related to the redefinition of fundamental notions of what constitutes a ‘disease.’ Nosology, the systematic classification of diseases, dates back to Carl Linnaeus, with the Genera Morborum Today, the improvement in our abilities to make molecular measurements related to health and disease has largely driven the revol...

Making it personal; mentoring future family docs.

Biomarkers for rheumatoid arthritis: making it personal.

Effective treatment of rheumatoid arthritis (RA) has been hampered by the heterogeneity of the disease. Although early intervention can result in disease remission, it requires early diagnosis - and current diagnostic tests are not sufficiently accurate or sensitive in the early stages of RA. As a result, RA is typically diagnosed only once damage to the joints has already begun, a time at whic...

Making connections

Kenney and Frankland. eLife 2014;3:e05504. DOI: 10.7554/eLife.05504 1 of 3 Autism spectrum disorders—such as Asperger syndrome and childhood autism—have long been known to have a significant genetic component (Ronald and Hoekstra, 2011). However, the biological basis of these disorders has remained largely elusive. Hundreds of genes have been linked to autism spectrum disorders (or ASDs), but m...

Making it Rich and Personal: Crafting an Institutional Personal Learning Environment

This view may not be reflected in the behaviour of those parts of a university which normally purchase and deploy technology infrastructure. These departments or services are slow to change because they are typically, and understandably, risk-averse; the more so, because the consequences of expensive decisions about infrastructure will stay with the organisation for many years. Furthermore acro...