Major Histocompatibility Complex–linked Control of Autoimmunity

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Major Histocompatibility Complex–linked Control of Autoimmunity

A lthough the MHC is a key genetic component in au-toimmune disease, our knowledge of the mechanisms by which the molecules encoded within the MHC influence autoimmune processes remains incomplete. Because of the linkage disequilibrium that exists among the class I, II, and III genes within the HLA complex in humans and the homologous MHC complex in rodents, the absolute contribution of the ind...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1997

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.186.7.973