Major Histocompatibility Complex Heterozygote Superiority during Coinfection
نویسندگان
چکیده
منابع مشابه
Major histocompatibility complex heterozygote superiority during coinfection.
Genes of the major histocompatibility complex (MHC) play a critical role in immune recognition, and many alleles confer susceptibility to infectious and autoimmune diseases. How these deleterious alleles persist in populations is controversial. One hypothesis postulates that MHC heterozygote superiority emerges over multiple infections because MHC-mediated resistance is generally dominant and m...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2003
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.71.4.2079-2086.2003