Major genetic components underlying alcoholism in Korean population
نویسندگان
چکیده
منابع مشابه
Major genetic components underlying alcoholism in Korean population.
Alcohol metabolism is one of the biological determinants that could significantly be influenced by genetic polymorphisms in alcohol-metabolism genes. Alcohol dehydrogenase (ADH) converts alcohol to acetaldehyde, and aldehyde dehydrogenase (ALDH) converts acetaldehyde to acetate. The well-known genetic polymorphisms in ADH1B(His47Arg) and ALDH2(Glu487Lys) have dramatic effects on the rate of met...
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Family, twin, and adoption studies have demonstrated that genes play an important role in the development of alcoholism. We investigated the association between alcoholism and the genetic polymorphisms of the GABAA receptor genes on chromosome 5q33-34 in Korean population. The genotype of the GABAA receptor gene polymorphisms were determined by performing polymerase chain reaction genotyping fo...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2007
ISSN: 1460-2083,0964-6906
DOI: 10.1093/hmg/ddm357