Macrophages - sensors and effectors coordinating skin damage and repair
نویسندگان
چکیده
منابع مشابه
UV damage, DNA repair and skin carcinogenesis.
Skin cancer is unique among human cancers in its etiology, accessibility and the volume of detailed knowledge now assembled concerning its molecular mechanisms of origin. The major carcinogenic agent for most skin cancers is well established as solar ultraviolet light. This is absorbed in DNA with the formation of UV-specific dipyrimidine photoproducts. These can be repaired by nucleotide excis...
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Influx of macrophages plays a crucial role in tissue repair. However, the precise function of macrophages during the healing response has remained a subject of debate due to their functional dichotomy as effectors of both tissue injury and repair. We tested the hypothesis that macrophages recruited during the diverse phases of skin repair after mechanical injury exert specific functions to rest...
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ژورنال
عنوان ژورنال: JDDG: Journal der Deutschen Dermatologischen Gesellschaft
سال: 2014
ISSN: 1610-0379
DOI: 10.1111/ddg.12290