منابع مشابه
Macrophage-melanocyte Heterokaryons
High yields of mouse macrophage-melanocyte heterokaryons and macrophage-macrophage homokaryons were obtained through the virus-induced fusion of cells spread on a glass surface. After fusion there was a striking reorganization of cellular architecture by means of a colcemid-sensitive process. Heterokaryons were isolated through the use of differential trypsinization and many underwent division ...
متن کاملMacrophage-melanoma Cell Heterokaryons
Mouse peritoneal macrophages possess a specific plasma membrane receptor for antibody-coated particles. Sheep red cells coated with rabbit 7S antibody attach readily to the macrophage surface and are subsequently interiorized. The fusion of macrophage with nonphagocytic mouse melanoma cells produces heterokaryons in which the macrophage receptor is drastically altered. The receptor is present s...
متن کاملPresumptive heterokaryons in Aspergillus fonsecaeus.
Raper and Fennell (1953) studied heterokaryon formation in Aspergillus fonsecaeus Thom and Raper, strain NRRL 67, a carbonaceous black species of the Aspergillus niger group (Thom and Raper, 1945) which produces large multinucleate conidia. Eleven various color, nutritional and morphological mutants (figure. 1) were produced by ultraviolet irradiation of the wild strain. The mutants were paired...
متن کاملAcquired melanocyte stimulating hormone-inducible chemotaxis following macrophage fusion with Cloudman S91 melanoma cells.
Fusion of Cloudman S91 melanoma cells with macrophages results in hybrids with increased metastatic potential. Here, we report that such hybrids acquire new pathways for motility. Compared to parental melanoma cells and low metastatic hybrids, the metastatic hybrids showed far stronger responses to 3T3- and lung fibroblast-conditioned media, primary lung slices, fibronectin (FN), and a Mr 120,0...
متن کاملNuclear Distribution in Conidia of Neurospora Heterokaryons.
N Neurospora heterokaryons with two genetically different kinds of nuclei, some I of the macroconidia are heterokaryotic and some are homokaryotic for either of the nuclear types. The relative frequencies of these three classes of conidia can be found experimentally if suitable genetic markers are present in the nuclei. It is reasonable to suppose that these frequencies are related both to the ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1971
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.133.2.321