Macrophage Depletion AbatesPorphyromonas gingivalis–Induced Alveolar Bone Resorption in Mice
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چکیده
منابع مشابه
Macrophage depletion abates Porphyromonas gingivalis-induced alveolar bone resorption in mice.
The role of the macrophage in the immunopathology of periodontitis has not been well defined. In this study, we show that intraoral inoculation of mice with Porphyromonas gingivalis resulted in infection, alveolar bone resorption, and a significant increase in F4/80(+) macrophages in gingival and submandibular lymph node tissues. Macrophage depletion using clodronate-liposomes resulted in a sig...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2014
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1400853