Macrolide resistance in Streptococcus species
نویسندگان
چکیده
منابع مشابه
Macrolide Resistance in Streptococcus pneumoniae
Streptococcus pneumoniae is a common commensal and an opportunistic pathogen. Suspected pneumococcal upper respiratory infections and pneumonia are often treated with macrolide antibiotics. Macrolides are bacteriostatic antibiotics and inhibit protein synthesis by binding to the 50S ribosomal subunit. The widespread use of macrolides is associated with increased macrolide resistance in S. pneum...
متن کاملSignificance of macrolide resistance in Streptococcus pneumoniae.
Sir, We wish to comment on the paper by Van Kerkhoven et al.,1 to dispel certain misconceptions that may arise from a cursory review of their study. The authors present a 3 year retrospective chart review of patients hospitalized with pneumococcal bacteraemia at a single hospital. Of the 136 patients identified, 14 (10.3%) and 33 (24.3%) had isolates non-susceptible to penicillin and erythromyc...
متن کاملAntimicrobial susceptibility and analysis of macrolide resistance genes in Streptococcus pneumoniae isolated in Hamadan
Objective(s): Macrolide resistant Streptococcus pneumoniae pose an emerging problem globally. The aim of this study was to investigate the prevalence of ermB and mefA genes (macrolide resistant genes) by polymerase chain reaction (PCR) method and to detect drug resistance patterns of S. pneumoniae isolated from clinical samples to macrolides and other antibiotic agents by E-test method. Materia...
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CONTEXT Macrolide antibiotics, including erythromycin, clarithromycin, and azithromycin, are the mainstays of empirical pneumonia therapy. Macrolide resistance among Streptococcus pneumoniae, the most common cause of community-acquired pneumonia, is increasing in the United States. Whether resistance is a significant problem or whether macrolides remain useful for treatment of most resistant st...
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Erythromycin resistance rates among penicillin-susceptible Streptococcus pneumoniae were 38 and 92% among penicillin-intermediate and -resistant S. pneumoniae isolates from Hong Kong, respectively, and 27% (43 of 158) of the isolates showed the MLS(B) phenotype, and the majority carried the ermB gene; 73% (115 of 158) displayed the M phenotype, and all possessed the mef gene. The MLS(B) phenoty...
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ژورنال
عنوان ژورنال: Journal of Pharmacy and Bioallied Sciences
سال: 2015
ISSN: 0975-7406
DOI: 10.4103/0975-7406.155784