منابع مشابه
Evaluating micro- and macro-vascular disease, the end stage of atherosclerosis, in rat models.
Development of effective treatment or, more critically, preventative measures against atherosclerosis and cardiovascular disease will require animal models that mimic the disease processes seen in humans and permit identification of the genetic and physiological factors. The Rat is normally resistant to cardiovascular disease, but a number of genetic mutations make affected strains of rats high...
متن کاملPrevention for Micro- and Macro-Vascular Complications in Diabetic Patients
One of the goals in long-term cares for patients with diabetes mellitus (DM) is to prevent the development of micro-and macrovascular complications (The International Diabetes Federation, 2011). To achieve this purpose, an adequate control of blood pressure (BP) as well as a good glycaemic control is crucial (The International Diabetes Federation, 2011). The American Diabetes Association recomm...
متن کاملCXCL16 in Vascular Pathology Research: from Macro Effects to microRNAs.
Chemokines and their receptors have become significant factors in atherosclerosis research. CXCL16 is a multifunctional agent located on a separate locus to all other known chemokines and binds only to its "unique" receptor named CXCR6. As a scavenger receptor, adhesion molecule, and chemokine, it quickly became an interesting target in atherosclerosis research as all its functions have a role ...
متن کاملHomocysteine and vascular disease.
In my experience the largest individual group of sufferers from recurrent and especially incessant pericarditis have been those without recurrent effusions who are presumed, though rarely firmly demonstrated (as here), to have an immunopathy, and especially those who are ‘steroid hooked’. Indeed, there is some evidence that corticosteroid treatment has been necessary to initiate the cycle of re...
متن کاملAutophagy in vascular disease.
Autophagy is a reparative, life-sustaining process by which cytoplasmic components are sequestered in double-membrane vesicles and degraded on fusion with lysosomal compartments. Growing evidence reveals that basal autophagy is an essential in vivo process mediating proper vascular function. Moreover, autophagy is stimulated by many stress-related stimuli in the arterial wall to protect endothe...
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ژورنال
عنوان ژورنال: Practical Diabetes International
سال: 2002
ISSN: 1357-8170,1528-252X
DOI: 10.1002/pdi.323