M30. Cortical Thickness Patterns of Cognitive Impairment in Schizophrenia
نویسندگان
چکیده
منابع مشابه
Cortical thickness in schizophrenia
The current study provides a complete MRI analysis of thickness throughout the cerebral cortical mantle in patients with schizophrenia (SZ) and rigorously screened and matched unaffected relatives and controls and an assessment of its relation to psychopathology and subjective cognitive function. We analyzed 3D-anatomical magnetic resonance imaging data sets, obtained at 3 Tesla, from three dif...
متن کاملCognitive impairment in schizophrenia.
Cognitive functioning is moderately to severely impaired in patients with schizophrenia. This impairment is the prime driver of the significant disabilities in occupational, social, and economic functioning in patients with schizophrenia and an important treatment target. The profile of deficits in schizophrenia includes many of the most important aspects of human cognition: attention, memory, ...
متن کاملCognitive impairment in schizophrenia
Traditionally, significant cognitive impairment was thought to be evident only in elderly deteriorated patients with schizophrenia. However, over the past 25 years, evidence has accrued to challenge this view. It is becoming evident that marked cognitive impairment is, in fact, the norm and often pre-dates the illness. The recent literature has attempted to characterise the prevalence, degree a...
متن کاملCognitive impairment patterns in schizophrenia and affective disorder.
A battery of neuropsychological tasks was used to study 62 schizophrenics, 67 melancholics, and 30 manics satisfying specific research diagnostic criteria, and 42 normal subjects. Two patterns of neuropsychological impairment among patients were identified by factor analysis. The first pattern of bifrontal, non-dominant hemisphere dysfunction was shared by schizophrenics and affectively ill pat...
متن کاملReduced cortical thickness in first episode schizophrenia.
OBJECTIVE Previous morphometric studies are suggesting altered cortical thickness mainly in prefronto-temporal regions in first episode schizophrenia. In an extension of these earlier studies, we used an entire cortex vertex-wise approach and an automated clustering for the detection and exact quantification of cortical thickness alterations in first episode schizophrenia. METHODS A group of ...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2017
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sbx022.029