Lymphoma developing during clozapine therapy

Agranulocytosis during Clozapine Therapy

Sir, This is in response to the article' Do Indian researchers read Indian research? a reappraisal, four years later', published in April 2000 (No.2, f Vol.42) issue of your journal. The authors of this article have documented their observations on my article 'Transsexualism in Schizophrenia : a case report' (April, 1998, Vol.40, No.2) that I did not refer to their article, 'Behaviour Therapy f...

Is Monitoring of Platelets Necessary during Clozapine Therapy ?

Sir, The availability of clozapine in India at prices relatively lower than those in the west has made this a feasible treatment option for many patients with schizophrenia or schizoaffective disorder whose illness had not responded to conventional treatment. However, it is still an expensive treatment, added to which are the costs of haematological monitoring. In order to minimise treatment co...

Rechallenge with clozapine following leucopenia or neutropenia during previous therapy.

BACKGROUND Further treatment with clozapine is contraindicated in any patient who has previously experienced leucopenia or neutropenia during clozapine therapy. AIMS To investigate the results of such a rechallenge in 53 patients. METHOD An analysis was made of the demographic, haematological and outcome data of patients in the UK and Ireland who were rechallenged with clozapine following l...

Thyrotoxicosis developing during cyclophosphamide therapy.

Acute crescentic glomerulonephritis developing during warfarin therapy.