Luteinizing hormone derivatives with covalently-linked subunits

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Subunits of luteinizing hormone from human pituitary glands.

Three species of luteinizing hormone (LH) designated as LH-A, -B, and -C, and containing 9, 8, and 4 NIH-LH-Sl units per mg were isolated from human pituitary glands by isoelectric focusing. The LH-A, -B, and -C each sedimented as a single boundary in the ultracentrifuge with ~20,~ of 2.34, 2.24, and 2.70 S, respectively. Amino acid analyses of LH-A, -B, and -C were very similar, although minor...

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background: luteinizing hormone (lh) was secreted by the stimulating cells of the testes and ovaries in the anterior pituitary gland. the application of this hormone is in the treatment of men and women with infertility and amenorrhea respectively. m aterials and methods: in the present study the alpha and beta subunits of human lh gene were cloned into the pegfp-n1 expression vector and produc...

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*Correspondence: Matthew A. Addicoat, Engineering and Science, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany e-mail: [email protected]; Manuel Tsotsalas, Institute of Functional Interfaces (IFG), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, Eggenstein-Leopoldshafen 76344, Germany e-mail: [email protected] In this review, we intend ...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1974

ISSN: 0014-5793

DOI: 10.1016/0014-5793(74)80730-1