Lubiprostone In Chronic Idiopathic Constipation: A Cost-Effectiveness Analysis
نویسندگان
چکیده
منابع مشابه
Lubiprostone: a novel treatment for chronic constipation
Chronic constipation is highly prevalent, reduces patients' quality of life, and imposes a significant health care burden on society. Lifestyle modifications and over-the-counter agents improve symptoms of constipation in some patients, however many patients have persistent symptoms and require the use of prescription medications. Three prescription medications are currently Food and Drug Admin...
متن کاملA critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly
Chronic constipation is a common disorder in the general population, with higher prevalence in the elderly, and is associated with worse quality of life and with greater health care utilization. Lubiprostone is an intestinal type-2 chloride channel activator that increases intestinal fluid secretion, small intestinal transit, and stool passage. Lubiprostone is currently approved by the US Food ...
متن کاملCost effectiveness of levocetirizine in chronic idiopathic urticaria : a pooled analysis of two randomised controlled trials.
BACKGROUND Chronic idiopathic urticaria is a distressing condition that severely affects patients' quality of life. The overall costs associated with this disease, both for the healthcare payer and society, are unknown. The objective of this study was to evaluate the cost effectiveness of levocetirizine, a first-line treatment for urticaria. METHODS Data were collected from two placebo-contro...
متن کاملSevere chronic constipation of young women: 'idiopathic slow transit constipation'.
A series of 64 women complaining of severe constipation is described, in each of whom delayed elimination of markers from the colon was demonstrated but a barium enema was normal. All completed a detailed questionnaire and the responses are compared with those obtained in an age-matched series of healthy women with no bowel complaint. In each group 40 women also recorded in a manner suitable fo...
متن کاملA Randomized Study of Lubiprostone for Opioid-Induced Constipation in Patients with Chronic Noncancer Pain
OBJECTIVE To evaluate the efficacy and safety of oral lubiprostone for relieving symptoms of opioid-induced constipation (OIC) in patients with chronic noncancer pain. DESIGN Prospective, randomized, double-blind, placebo-controlled trial. SETTING Seventy-nine US and Canadian centers. SUBJECTS Patients aged ≥ 18 years with OIC, defined as <3 spontaneous bowel movements (SBMs) per week. ...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2014
ISSN: 1098-3015
DOI: 10.1016/j.jval.2014.08.817