Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response

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Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response

Clozapine has been consistently shown to be superior to other antipsychotics in the treatment of psychosis. However, clozapine usage has been limited due to required routine blood monitoring and the potential for life threatening side effects. We report a case of a 66-year-old female patient, who developed clozapine-induced agranulocytosis after 10 weeks of clozapine treatment and was subsequen...

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Clozapine for mitochondrial psychosis☆

With interest we read the article by Demily et al. about a 30 year old male with neuropathy, ataxia, and retinitis pigmentosa (NARP) syndrome due to the mutation m.8993TNC, clinically manifesting as cerebellar ataxia, pyramidal syndrome, and psychosis [1]. Upon antipsychotic medication the patient developed dystonia, akathisia, and extrapyramidal symptoms with falls [1]. Switching to clozapine ...

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Cerebrovascular disease is a cause of late-onset psychosis in the elderly more frequent, accompanied or not, multi-infarct dementia. In many cases the patient has adequate preservation of cognitive functions or in any case, no criteria for dementia. In those that do, is in vascular dementia where psychotic symptoms are more frequent, occurring in over half cases, compared to one third of patien...

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We thank Drs J. Finsterer and S. Zarrouk-Mahjoub [1] for their comments regarding our report [2] on the beneficial effects of low dose clozapine for management of psychotic symptoms in a patient with neurogenic ataxia-retinitis pigmentosa (NARP mutation, m.8993TNC, maternally inherited from asymptomatic carrier mother). We agree that clozapine has many side effects, some of them being potential...

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ژورنال

عنوان ژورنال: Case Reports in Psychiatry

سال: 2016

ISSN: 2090-682X,2090-6838

DOI: 10.1155/2016/6123913