Lowering of Blood Pressure in Sympathectomized Spontaneously Hypertensive Rats on Beta Adrenoreceptor Blockade
نویسندگان
چکیده
منابع مشابه
α2-Adrenoreceptor Constraint of Catecholamine Release and Blood Pressure Is Enhanced in Female Spontaneously Hypertensive Rats
UNLABELLED α2-adrenoceptors (α2AR) lower central sympathetic output and peripheral catecholamine release, and may therefore prevent sympathetic hyperactivity and hypertension. The α2AR are dysfunctional in male spontaneously hypertensive rats (SHR). Premenopausal females are less hypertensive than males. The purpose of this study was to test if this difference could be explained by functional α...
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1. Sensitivity of the sino-aortic baroreflex was investigated before and after acute (23 patients) and chronic (23 patients) beta-adrenoreceptor antagonism in patients with essential hypertension. 2. Sensitivity was inversely related to age (r = -0.60) and systolic blood pressure (r = -0.46); a positive relationship was noted between sensitivity and initial pulse intervals (r = 0.40). 3. Sensit...
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The present study examines effects of administration of OKY 046, an inhibitor of thromboxane synthesis, for 100 days on systemic blood pressure and renal function in spontaneously hypertensive rats and in normotensive control rats. Untreated spontaneously hypertensive rats had higher values for thromboxane excretion in the urine and higher values for blood pressure than did normotensive control...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 1979
ISSN: 0021-4868,1348-673X
DOI: 10.1536/ihj.20.726